Clinical Case Question: A patient reports progressive weakness, tingling, and numbness in both hands and feet. What condition is most likely causing this polyneuropathic syndrome?

Clinical Case Question: A patient reports progressive weakness, tingling, and numbness in both hands and feet. What condition is most likely causing this polyneuropathic syndrome?

Correct answer is B. Guillain-Barré syndrome (GBS) is a condition characterized by acute polyneuropathy, leading to symmetrical weakness, tingling, and numbness in the extremities. The symptoms typically start in the feet and hands and can progress upwards. It is crucial for medical practitioners to recognize this acute, symmetric, ascending pattern of weakness and sensory disturbances associated with GBS, as prompt diagnosis and treatment are essential. Options (a), (c), and (d) describe conditions that are not typically associated with the diffuse, symmetric involvement of peripheral nerves seen in polyneuropathic syndromes like GBS.

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