Generalized fasciculations are a key sign in the diagnosis of motor neurone disease. Which of the following statements is true regarding the observation and significance of fasciculations?

Fasciculations, which are involuntary muscle twitches, can be a key sign in diagnosing motor neurone disease (MND). However, they are not exclusively indicative of MND and can be observed in normal individuals, particularly in the triceps, calves, and tongue. The presence of fasciculations alone, without accompanying symptoms such as muscle wasting, weakness, or changes in reflexes, is generally not a cause for concern. Therefore, a thorough examination of the entire musculature is essential when considering a diagnosis of MND to differentiate between benign fasciculations and those associated with more serious conditions.